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Nutrition

Gluconeogenesis

Gluconeogenesis is liver production of glucose from non-carb substrates. It stabilizes blood sugar during fasting and low-carb training but needs adequate protein to protect muscle.

Gluconeogenesis is the liver’s process of making new glucose from non-carb sources—amino acids, lactate, glycerol—when carbs are low or demand is high. It keeps blood sugar stable during fasting, hard training, and low-carb phases.

Excessive reliance without adequate protein can cost lean mass. Ohga flags very low carb plus high training load when recovery scores drop, suggesting you review protein and meal timing before blaming “keto flu.

Common questions

  • Does gluconeogenesis break down muscle?

    It can use amino acids when protein is inadequate and carb restriction is extreme. Keep protein at 1.6 g/kg or above on low-carb training blocks to limit muscle loss.

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